问鼎娱乐

徐立

发布时间: 2021-03-30 21:25:16 已阅读:

 


徐立,博士,副教授,硕士生导师

简历

1996 - 2000 西南农业大学,蚕丝生物科学,学士;

2000 - 2003 西南农业大学,特种经济动物饲养,硕士;

2000 - 2003 西南大学,特种经济动物饲养,博士;

2004 - 2006 中科院昆明植物所植物化学国家重点实验室,客座博士研究生;

2006 - 至今 西南大学,教师;

2015 - 2016新加坡国立大学食品系,访问学者。

主要研究领域

1.植物次生代谢产物的分离鉴定、活性(抗衰老、美白、抗炎、降三高、抗病毒、抗菌、抑制阿尔兹海默症等)评价、作用机制研究及相关产品开发;

2.植物细胞培养(生物合成护肤与医药领域急需重要次生代谢产物)。

主要科研成果

主持和参研40余项科研课题;

以第一发明人申请国家发明专利20

在国内外学术刊物发表论文90余篇(第一作者或通讯作者70余篇)。

所获荣誉

2022年获“2020-2022学年度优秀教师”;

2018年获“2016-2018学年度优秀教师”;

2016年获“重庆市第七届科慧杯研究生创新创业大赛优秀指导

2012“第二届西南大学教学成果一等奖”(4/5

2011年获“20102011年度农业部“中华农业科技奖”二等奖”(12/15

2011“西南大学第六届教师课堂教学比赛”优秀奖;

2007年获“教育部科技进步奖(推广类)二等奖11/12

指导学生参加“创业大赛”、“挑战杯”比赛,获得“国家银奖”、国家铜奖”、“国家三等奖”、“重庆市金奖”、“重庆市特等奖”等奖项。

社会/学术兼职

全国万名优秀创新创业导师;

国家、重庆市“三区”科技特派员;

Industrial Crops and Products, Journal of agriculture and food chemistry, RSC Advances, Pharmaceutical Biology, Biomedicine & Pharmacotherapy, Food & Function, Phytomedicine, 天然产物研究与开发, 天然产物化学,等国内外多家刊物审稿人Journal of Functional Biomaterials 客座编辑。

代表性学术论文

Yurong Li, Long Guo, Juanjuan Wei, Yijun Yao, Li Xu *, Zhiqin Zhou*.Effect of polyethoxylated flavonoids (PMFs)-loaded citral and chitosan composite coatings on citrus preservation: From the perspective of fruit resistance[J] Food Chemistry: X, 2024,(22):101417(一区,TOP

Shanshan Liu , Xiaowen Shi, Wei Xiang*, Zhihui Jin, Yanan Jia, Yuansong Zhang, Lingshu Zeng, Jiaxin Chen, Xianzhi Huang, Li Xu*Bioactivities and physicochemical properties of crude polysaccharides from mulberry twigs, agricultural by-products[J] Industrial Crops & Products, 2023, (193):116191(一区,TOP

Xiaowen Shi , Li Xu,*, Jianqin Zhang, Juanfen Mo , Pei Zhuang, Li Zheng*. Oxyresveratrol from mulberry branch extract protects HUVECs against oxidized Low-density Lipoprotein-induced oxidative injury via activation of the Nrf-2/HO-1 pathway[J] Journal of Functional Foods, 2022, (100):105371.(二区,TOP

Pingkang Xu· Qimin Chen· Xiaoman Chen· Hao Qi· Yuyan Yang· Weiqi Li· Xin Yang· Amelia Gunawan· Shuoyu Chen· Huimin Zhang· Han‑Ming Shen· Dejian Huang Brian Kennedy Li Xu*·Ziyun Wu*. Morusin and mulberrin extend the lifespans of yeast and C. elegans via suppressing nutrient‑sensing pathways[J] Gero Science, 2022,45):949-964(一区,TOP

Fanshan Feng, Wei Xiang*, Han Gao, Yanan Jia, Yuansong Zhang, Lingshu Zeng, Jiaxin Chen, Xianzhi Huang, Li Xu*. Rapid Screening of Nonalkaloid α-Glucosidase Inhibitors from a Mulberry Twig Extract Using Enzyme-Functionalized Magnetic Nanoparticles Coupled with UPLC-MS/MS[J] Journal of Agricultural and Food Chemistry, 2022, (70):11958-11966(一区,TOP

Yuyuan Zhu , Wei Xiang, Yao Shen, Yanan Jia, Yuansong Zhang, Lingshu Zeng, Jiaxin Chen, You Zhou, Xin Xue, Xianzhi Huang, Li Xu*. New butyrylcholinesterase inhibitor derived from mulberry twigs, a kind of agricultural byproducts [J] Industrial Crops & Products, 2022, (187):11535(一区,TOP

Lin He, Feifei Huang, Yu Wang, Yijun Wu , Li Xu * and Pingan Chang. The Catalytic Domain of Neuropathy Target Esterase Influences Lipid Droplet Biogenesis and Lipid Metabolism in Human Neuroblastoma Cells[J] Metabolites, 2022, (12): 637.

Wei Xiang, Zhining Xia, Li Xu*. UPLC-MS/MS Profiling, Antioxidant, α-Glucosidase Inhibitory, Cholinesterase Inhibitory, and Cardiovascular Protection Potentials of Jialing 20 (Morus multicaulis Perr.) Mulberry Branch Extract [J] Foods, 2021, 10, 2659. Jing Liu1, Yan Yu, Yiping Zhao, Liangyu Jiang, You Zhou, Dejian Huang, Li Xu. Interrelation of cholesterol-lowering, antioxidant activity and DNA damage protection to the different solvent extracts of mulberry (Morus alba L.) [J] Journal of food processing and preservation, 2020, 45(1): e14891

Ya-Nan Jia, Ya-Lin Peng, Yi-Ping Zhao, Xi-Fei Cheng, You Zhou, Chun-Li Chai, Ling-Shu Zeng, Min-Hui Pan, and Li Xu*Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs[J] Journal of Agricultural and Food Chemistry,2019, (67)5521-5529

成希飞杨沙陈果,赵一萍,彭娅林,周游,徐立*. 两种酶水解制备丝素肽的抗菌性及对人胚肾细胞的毒性分析[J] 食品与发酵工业, 2017, 45(6):115-121

Ya-Nan Jia, Hai-Peng Lu, Ya-lin Peng, Bao-Shun Zhang, Xiao-bao Gong, Jun Su, You Zhou, Min-Hui Pan, Li Xu*. Oxyresveratrol prevents lipopolysaccharide/d galacto- samine induced acute liver injury in mice[J] International Immunopharmacology,2018, (56):105-112

Hai-Peng Lu, Ya-Nan Jia, Ya-Lin Peng, Yan Yu, Si-Long Sun, Meng-Ting Yue, Min-Hui Pan, Ling-Shu Zeng and Li Xu*. Oxyresveratrol, a Stilbene Compound from Morus alba L. Twig Extract Active Against Trichophyton rubrum[J] Phytotherapy Research, 2017, (31):1842-1848

Hai Peng Lu, Ya Nan Jia, Yan Yu, and Li Xu*. DNA Protection Activity of a Hydroethanol Extract and Six Polyphenol Monomers from Morus alba L. (Mulberry) Twig [J] International Journal of Food Properties, 2017, 20(S2):S2207-S2219

贾亚楠,逯海朋,喻艳,刘欣瑾,陈伟,曾令树,徐立*. 桑枝内生菌代谢产物抑制α-葡萄糖苷酶和抗氧化活性研究[J] 食品与发酵工业, 2017, 43(11):132-139

喻艳,逯海朋,贾亚楠,向伟,粟君,曾令树,敬成俊,王茜龄,徐立*. 桑椹中酚类物质极性分布及抗氧化活性评价[J] 食品与发酵工业, 2017, 43 (1) :73-79

, 喻 艳, 刘 静, *, 丁天龙, 左少纯. 新疆药桑枝条中抗氧化活性成分sanggenon A[J]. 林业科学, 2016,52(3):30-35

Chao Liu, Wei Xiang, Yan Yu, Zhengqin Shi, Li Xu*. Comparative analysis of 1-deoxynojirimycin contribution degree to α-glucosidase inhibitory activity and physiological distribution in Morus alba L [J]. Industrial Crops and Products, 2015, 70: 309–315. (一区,TOP

, 史正琴, 向 伟, *, 兰 俊. 桑枝1-脱氧野尻霉素的提取及其含量与α-葡萄糖苷酶抑制活性的相关性分析[J]. 林业科学, 2015, 51(2): 112-120.

, 刘 静, 谷少伟, 左少纯, *. 新疆药桑中稀有黄酮Sanggenon M的分离鉴定及其抗氧化活性[J]. 食品科学, 2015,36(21):37-40.

史正琴, 刘 超, 向 伟, 喻 艳, *. 桑树不同部位的γ-氨基丁酸含量测定及提取条件优化[J]. 蚕业科学, 2015, 41(5):0908-091.

Li Xu*, Chao Liu, Wei Xiang, Chen Hu, Xiaoli Qin, Xianzhi Huang. Advances in the study of oxyresveratrol. International Journal of Pharmacology, 2014, 10(1): 44-54.

Chao Liu, Chuan-hong Wang, Jing Liu, Li Xu*. Optimization of microwave-assisted technology for extracting 1-deoxynojirimycin from mulberry tea by response surface methodology [J]. Food Science and Technology Research, 2014, 20(3): 599-603.

Li Xu *, Chuanhong Wang, Chao Liu, Jing Liu, Wei Xiang. Antioxidant activity and total flavonoids of silkworm excrement extracts [J]. Journal of current research in science, 2014, 2(2): 264-267.

Wang chuan-hong, Liu Chao, Liu Jing, Xiang Wei, Xu Li*. Study on Antioxidant Activity of Medicine mulberry (Morus nigra L.) [J]. Scienta Silvae Sinicae, 2014, 50(8): 53-59.

, *, 刘 静, 郑曼. 桑枝提取物中1-脱氧野尻霉素的稳定性研究[J]. 食品科学, 2014,35(23): 52-56.

Li Xu*, Jing Liu, Chao Liu, Chun Wu, Chuan-Hong Wang, Xian-Zhi Huang. Response surface optimization of ultrasonic-assisted oxyres- veratrol extraction from the bark of cultured black mulberry (Morus nigra L.) [J]. Separation Science and Technology, 2013, 48: 2779–2785.

, 刘 超, 王传宏, *, 向 伟, 明 月, 吴丽莉, 丁天龙. 新疆药桑枝条醇提物不同溶剂萃取组分的抗氧化活性物质含量及抗氧化活性测试[J]. 蚕业科学, 2013, 39(5): 120-125.

Wu Chun, Xu Li*, Wang Yuancheng, Chen Hu and Huang Xianzhi. Determination of total polyphenol content and antityrosinase capacity of medicine mulberry (Morus nigra L.) extract [J]. African Journal of Biotechnology, 2011, 10(72): 16175-16180.

王元成, 伍 春, 陈 虎, 郑 颖, *,. 桑白皮中白藜芦醇、氧化白藜芦醇和桑皮苷的抗氧化活性研究[J]. 食品科学, 2011,32(1):135-138.

, *, 余茂德, 刘峻池, 黄先智. 新疆药桑桑枝中桑色素的提取分离及鉴定[J]. 食品科学, 2011, 32(2): 76-78.

, *, 刘峻池, 黄先智, 买买提依明. 响应曲面法优化新疆药桑桑皮总多酚提取工艺[J]. 食品科学, 2011, 32(2): 104-107.

刘峻池, *, 伍 春, 余茂德. 四倍体果桑新品种嘉陵30号桑椹中的氨基酸组成及其含量分析[J]. 蚕业科学, 2011, 37(1): 112-118.

, *, 周 林, 刘峻池, 余茂德, 黄先智, 夏玉玲. 几个果桑品种桑椹中的主要抗氧化活性物质含量比较[J]. 蚕业科学, 2010, 36(2): 0337-0340.

, *, 伍 春, 余茂德, 黄先志. 桑枝皮总黄酮的提取工艺优化[J]. 蚕业科学, 2010, 36(3): 491-495.

, 稽长久, 谭宁华, 杨利荣, 余茂德*. 桑树活性黄酮Norartocarpetin的分离鉴定[J]. 食品科学, 2010, 31(5): 101-103.

, 周 林, 伍 春, 刘俊池, 余茂德*, 肖 伟. 超声波法提取桑根皮中桑皮素A的工艺研究[J]. 食品科学, 2009, 30(24): 144-147.

吴石磊, *, 刘 俊, 周 林, 伍 春, 刘峻池, 肖 伟, 余茂德. 桑皮苷的提取方法及工艺条件研究[J]. 蚕业科学, 2009, 35(3): 671-674.

, 余茂德*, 王茜龄, 夏庆友, 稽长久, 谭宁华,杨利荣, 何 敏. 桑树中稀有木质素Dadahol A的分离鉴定[J]. 蚕业科学, 2008, 34(1): 88-91.

,稽长久, 谭宁华, 余茂德*, 王茜龄, 夏庆友. 桑树中东莨菪素及东莨菪苷的分离鉴定[J]. 蚕业科学, 2008, 34(4): 593-599.

出版学术专著:

参编《中国农作物病虫害》(第三版),中国农业出版社,2015

联系方式:

问鼎娱乐-问鼎官网 应用生物技术研究室
电 话:17774944258
传 真:023-68250191
E – mail :[email protected]; [email protected]